The recent $38 billion agreement signed by Amazon and OpenAI is an interesting turning point for the marketplace world and for all sellers present on the platform. The strategic partnership allows OpenAI to use Amazon Web Services (AWS) data centers to power its artificial intelligence systems, leveraging hundreds of thousands of Nvidia chips specialized for AI.
With these premises, it is fair to think that this agreement will have profound implications for the future of the marketplace and for the tools available to sellers. Amazon’s massive investment in AI infrastructure is indeed a clear signal of the direction the system will take in the coming years. Let’s try to share some reflections together.
What changes for Amazon sellers
The agreement with OpenAI should accelerate the development of advanced AI-based tools for Amazon sellers. Based on what can be considered today, it is possible that in the coming months or years we can expect:
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Even more precise demand forecasting systems. AI algorithms will be able to analyze purchasing patterns with even more sophisticated granularity. This will allow sellers to optimize inventories and reduce storage costs.
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Real-time price optimization tools. AI will be able to monitor competitors, demand, and even social media trends. By doing so, it will suggest dynamic pricing strategies that maximize margins.
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Semi-automated content creation. Sellers will have access to tools that generate product descriptions, answers to customer questions, and A+ content optimized for conversions. Effective personalization for specific customer segments will be achieved. However, automation is unlikely to exclude the active role of the seller in refining the “human” touch of listings.
>>> Read also our guide Amazon Inventory Management: guide to warehouse optimization <<<
What changes for the sales infrastructure
The agreement provides that all computing capacity will be deployed by the end of 2026, with expansion possibilities in 2027 and beyond. In this case too, the impacts are certainly not few. We hypothesize that the main changes should focus on:
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Faster data processing. Seller Central platform performance will improve. Reporting will become real-time and predictive analytics will be much more sophisticated.
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Process automation. Sellers will be able to automate many manual processes. For example, inventory management and customer service will undergo this fate. More resources will thus be freed up for higher value-added activities.
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Personalized customer experience. AI will allow creating hyper-personalized shopping experiences, increasing conversions and customer loyalty.
Let’s also recall that this agreement fits into a broader context of OpenAI investments in AI infrastructure. For example, OpenAI has employed over $1 trillion in AI-related projects with agreements with Oracle, SoftBank, and semiconductor suppliers like Nvidia, AMD, and Broadcom. An extraordinary level of investment, demonstrating how crucial computing power is for AI development and suggesting that Amazon is positioning AWS as the fundamental infrastructure for the next generation of AI solutions.
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What will happen now to Amazon sellers: our predictions
As a company that works every day with Amazon sellers, we can hypothesize some predictions about the sector. We believe in particular that this agreement can accelerate AI adoption in the marketplace in directions that could significantly change seller strategies. Let’s try to summarize the new optimization opportunities in this table, before talking about them more extensively.
|
Area |
Expected Impact |
Timing |
| Listing optimization | Advanced AI tools for keyword research and copy | 2025-2026 |
| Inventory management | Near-perfect demand forecasts | 2025-2026 |
| Advertising | Ultra-precise behavioral targeting | 2026 |
| Customer service | Virtual assistants indistinguishable from human operators | 2026-2027 |
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Listing optimization via Advanced AI
The Amazon-OpenAI agreement will bring changes in product listing optimization thanks to next-generation language models. The power derived from Nvidia chips in AWS data centers will allow sophisticated semantic analyses. And, therefore, the automatic identification of keywords with greater conversion potential. Sellers will have access to tools that will not only suggest keywords but will analyze in real time the linguistic patterns of customers who convert best.
It is therefore fair to imagine systems that will generate A/B variants of product descriptions. They will then analyze which narrative elements and text structures obtain the best results for specific categories and demographic segments. The AI will be able to personalize bullet points and technical descriptions based on user browsing behavior. And they will show first the aspects that most interest that particular buyer profile.
The tools will also integrate data from reviews to automatically identify which product features generate greater satisfaction, strategically incorporating them into the listing.

Inventory management with more precise predictions
Inventory management will undergo an evolution thanks to predictive models enhanced by the Amazon-OpenAI partnership. The new algorithms will overcome the limits of current forecasting systems. They will analyze not only historical sales data but will integrate external sources such as:
- social trends
- seasonal events
- regional climate changes
- real-time economic indicators.
The AI will be capable of predicting demand peaks with pinpoint accuracy. It will suggest optimal reorder quantities to balance stockout risk with warehouse costs. Sellers will have access to dashboards that will visualize multiple probabilistic scenarios. And, by doing so, they will be able to make more informed decisions on when to launch promotions to clear excess stock or when to increase orders in anticipation of peaks. Particularly important will be the ability of these systems to self-learn from their own errors. Over time, they will become increasingly accurate.
Advertising with more effective behavioral targeting
Advertising targeting on Amazon will benefit from the computing power provided by the agreement with OpenAI. The new targeting algorithms will thus succeed in analyzing complex behavioral patterns. And they will be able to predict purchase intent with very satisfactory precision. The AI will be able to identify buyers with a high probability of conversion even before they explicitly manifest their interest, based on navigation micro-behaviors and purchase history.
Advertising tools will integrate sophisticated sentiment analysis from comments and reviews. They will allow targeting not only based on demographic or behavioral data but also based on emotional nuances and stylistic preferences. Sellers will be able to access digital copies of their ideal customers. They will thus be able to create campaigns that address hyper-personalized behavioral profiles. The system will automatically optimize budgets, bids, and advertising creatives in real time. It will also manage to adapt to market fluctuations and maximize ROAS (Return on Ad Spend) with extremely high precision.
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Virtual assistants for customer service
The most visible innovation for consumers will be in the field of customer service. Here, in fact, the Amazon-OpenAI agreement will allow the development of virtual assistants practically indistinguishable from human operators. Advanced systems will overcome the limitations of current chatbots. They will in fact be able to understand linguistic nuances, sarcasm, and complex requests thanks to next-generation language models powered by the AWS infrastructure.
Virtual assistants will be able to instantly access a customer’s entire order and interaction history. Consequently, they will be able to offer personalized solutions and anticipate potential problems. They will be able to:
- autonomously manage the entire return process
- provide advice on product usage
- propose related items with accuracy superior to current recommendation systems.
For sellers, it is evident that all this constitutes an extraordinary opportunity to scale customer service without compromising quality, drastically reducing operational costs. The true added value will be in the ability of these systems to generate valuable insights from conversations with customers, identifying recurring product problems and opportunities for improvement.
>>> You can also read our article Reddit and AI Search: here is why Amazon sellers cannot do without this platform <<<
How to prepare for changes now
The most forward-looking sellers should already start to:
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Invest in data collection. The effectiveness of AI tools will depend on the quality of available data. Start collecting and organizing detailed data on your sales, customers, and performance.
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Train on AI technologies. Even a basic understanding of AI will allow leveraging new tools to the fullest when they become available.
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Experiment with existing tools. Amazon already offers some AI-based tools. Familiarizing yourself with these will give an advantage when more advanced versions arrive.
The agreement between Amazon and OpenAI is therefore an interesting commercial partnership that sellers should keep under control. It is indeed a clear indicator of the centrality that AI will have in the Amazon system in the coming years. Sellers who understand and embrace this transformation will certainly have a significant competitive advantage. We are moreover already observing how the first AI tools are producing superior results compared to traditional strategies. The agreement with OpenAI will only accelerate this trend. The agreement will in fact create an increasingly wide gap between technologically advanced sellers and those who resist change.
Our recommendation is therefore clear. Start preparing today for an Amazon system increasingly influenced by artificial intelligence. The future of online sales is already here, and it will be powered by AWS data centers and the computing power discussed in this historic agreement.

